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The Use of B-Type Natriuretic Peptides in the Intensive Care Unit
Christian Mueller, MD; Alan Maisel, MD; Alexandre Mebazaa, MD, PhD; Gerasimos S. Filippatos, MD

B-type natriuretic peptide levels are quantitative markers of cardiac stress and heart failure that summarize the extent of systolic and diastolic left ventricular dysfunction, valvular dysfunction, and right ventricular dysfunction. Initial observational pilot studies have addressed 7 potential indications in the intensive care unit: identification of cardiac dysfunction, diagnosis of hypoxic respiratory failure, risk stratification in severe sepsis and septic shock, evaluation of patients with shock, estimation of invasive measurements, weaning from mechanical ventilation, as well as perioperative and postoperative risk prediction. Although additional studies are required to better define the clinical utility of B-type natriuretic peptide values in the intensive care unit, current data suggest that the diagnosis of hypoxic respiratory failure and timing of extubation seem to be the most promising indications. Congest Heart Fail. 2008;14:XXX-XXX [ahead of print, issue not paginated].

Congest Heart Fail(2008) 14;4 Suppl 2:0

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Obstructive Sleep Apnea and Hypertension
The Journal of Clinical Hypertension^®

1.0 AMA/PRA Credit

Improving Blood Pressure Control: Increase the Dose of Diuretic or Switch to a Fixed-Dose Angiotensin Receptor Blocker/Diuretic? The Valsartan Hydrochlorothiazide Diuretic for Initial Control and Titration to Achieve Optimal Therapeutic Effect (Val-DICTATE) Trial
The Journal of Clinical Hypertension^®

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Varenicline and Its Role in Smoking Cessation
Preventive Cardiology™

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Salt-Resistant and Salt-Sensitive Phenotypes Determine the Sensitivity of Blood Pressure to Weight Loss in Overweight/Obese Patients
The Journal of Clinical Hypertension^®

1.0 AMA/PRA Credit

Challenges to the Diagnosis, Evaluation, Treatment and Management of Clustered Cardiometabolic Risk Factors
Journal of the CardioMetabolic Syndrome

1.0 AMA/PRA Credit

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